[ep149] an Automated and Minimally Invasive Tool for Generating Autologous, Viable, and Proliferative Epidermal Micrografts
نویسندگان
چکیده
Aim: Skin grafts are often performed to treat chronic wounds including venous leg, diabetic foot, and pressure ulcers. Although traditional skin grafting has been successful for many years, it is often associated with donor site damage, and necessitates a surgical suite. In this IRB-approved study, an epidermal harvesting tool* was used to create epidermal grafts from 12 healthy human subjects. Epidermal grafts were assessed for uniform viability and formation at the dermal/epidermal (DE) junction.
منابع مشابه
An Automated and Minimally Invasive Tool for Generating Autologous Viable Epidermal Micrografts
OBJECTIVE A new epidermal harvesting tool (CelluTome; Kinetic Concepts, Inc, San Antonio, Texas) created epidermal micrografts with minimal donor site damage, increased expansion ratios, and did not require the use of an operating room. The tool, which applies both heat and suction concurrently to normal skin, was used to produce epidermal micrografts that were assessed for uniform viability, d...
متن کاملEpidermal Micrografts Produced via an Automated and Minimally Invasive Tool Form at the Dermal/Epidermal Junction and Contain Proliferative Cells That Secrete Wound Healing Growth Factors
OBJECTIVE The aim of this scientific study was to assess epidermal micrografts for formation at the dermal-epidermal (DE) junction, cellular outgrowth, and growth factor secretion. Epidermal harvesting is an autologous option that removes only the superficial epidermal layer of the skin, considerably limiting donor site damage and scarring. Use of epidermal grafting in wound healing has been li...
متن کاملThe increasing role of epidermal grafting utilizing a novel harvesting system in chronic wounds.
Skin grafting techniques range from harvesting full-thickness to split-thickness grafts to grafts containing only epidermis. All of these autologous tissues have their place on the reconstructive ladder. However, the use of full-thickness and split-thickness grafts as coverage over chronic wounds remains limited by a number of factors, including the need for anesthesia, a surgically trained phy...
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Vitiligo is a common pigmentary disorder of the skin with a great amount of social stigma attached to it. Though various medical modalities are available for the treatment of stable vitiligo, surgical modality remains the treatment of choice for stable and localized vitiligo. The surgical options range from simple punch grafting to the recent epidermal harvesting methods using a negative pressu...
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